Yes, if you are using a genuine data recovery software it will be totally safe to use. However always beware of fake cracks and keygens. A genuine data recovery software will only read your drive for traces of lost or deleted files and will never alter them. You can be sure that if you a using a good software your data will be secure and retrieved without any issues or adverse system damage. You can give a try to some trusted recovery software such as Stellar, recuva and Ontrack. These software have been verified by sources such a PC Mag and Cnet.