Yes, cruise itineraries are subject to change. Various factors can lead to adjustments in a cruise schedule, including:

1. Weather Conditions: Storms, rough seas, or other adverse weather conditions can force a change in course for safety reasons.
2. Port Availability: Ports of call may be closed or unavailable due to unforeseen circumstances, such as local strikes, natural disasters, or maintenance.
3. Operational Issues: Mechanical problems with the ship or other logistical challenges can cause delays or changes to the planned itinerary.
4. Health and Safety: In rare cases, issues like illness outbreaks or changes in health regulations may lead to alterations in the cruise schedule.

Kimberley Cruise itineraries usually notify passengers in advance about any changes and often provide alternative options, but it's important to be aware that flexibility is essential when booking a cruise.