Yes, and the chips in the device you’re reading this answer on were almost certainly built in machines controlled by Smalltalk. Lam Research is the world’s leading manufacturer of wafer processing machines, and their machines are controlled using Smalltalk. Lower level sensorimotor components are programmed in C or real-time Java. But all higher-level control such as planning and scheduling activities (these are essentially industrial robots with electrochemical processors in them) is programmed in Smalltalk. Intel’s, Samsung’s and other fab plants use Lam machines. AMD has its own series of machines and these also use Smalltalk. Both Lam’s and AMD’s Smalltalk Systems derive from ControlWORKS, which was developed at Texas Instruments under DoD/DARPA funding, beginning in the late ‘80’s or early ‘90’s.