Yes - but f=ma is a special case of Newton's second law anyway.

The actual statement is:

[math]F = \frac{dp}{dt}[/math]

In a system where the mass stays the same during the acceleration, this simplifies to f=ma - but in relativity the act of accelerating changes the (relativistic) mass.

So yes - but there are many non-relativistic situations which also make this specific definition redundant (rockets which expel gases come to mind). However, the fundamental form is still valid.