Yes you can.

But why put this much strain on your System’s Hardware when there’s a simple way to achieve the same result.

Solution: Make a Image of the CD/DVD and mount it to a Virtual Drive

1. Go to any System which has working CD/DVD drive.
2. Put your CD/DVD inside the Reader.
3. Run any imaging software like Daemon tools, PowerISO and select create a Image of CD/DVD option.
4. Wait till the process completes. After completion you will get a Image (.iso) file of the CD/DVD. This Image file will be of same size (it may differ by some MB or KB) as of your CD/DVD.
5. Now If you have Windows 8 & above, you can right click and select Mount option from the Menu. That will open the image file in same way as your CD/DVD Reader would have opened.
6. If you are running Windows 7 or below then you need to create a Virtual drive using Daemon tools or PowerISO then mount the image file to that Virtual drive.
7. Now just go ahead and launch the game, it will run without any issues.

Advantages:

Don’t need to always put CD/DVD inside the Reader. Saves the hardware.

You don’t need to buy external CD/DVD Reader.

Imaging is one time task and Image file can be transferred from one system to another.

Goodluck !!!