That Windows desktop's "Refresh" button is not some magical tool which keeps your computer healthy.

What does a desktop refresh actually do? Refreshing the desktop simply redraws the icons on the desktop. That's it! It doesn't refresh the RAM. It doesn't clean your PC. It doesn't refresh your computer the way it refreshes you when you wake up from a nap. Refreshing the desktop has absolutely no effect on the performance of the computer.