Important Links

• Infectious Lecture Notes - Eneutron
• Next Lecture Notes - Legionellosis
• Previous Lecture Notes - Hemorrhagic Fever

—————————————————————————————————————

Overview :

It is an infectious disease characterized by Central Nervous System wrilation followed by paralysis and death

Etiology :

1. Causative agent - Rhabdoviruses
2. Mechanism of transportation - Bites

Clinical Features :

1. Incubation period : 20-90 days
2. Fever, changes of mood, flu like symptoms
3. Hydrophobia, Aerophobia
4. Spasms affect diaphragm, sternomastoideus
5. Hyper salivation, lacri-motion, sweating, fluctuating blood pressure
6. Furious Rabies progress to coma and later death

Diagnosis :

1. Immunofluroscence of acetone fixed brain or spinal cord impression smears
2. ELISA test
3. Examination of CNS tissue
4. Neutrophil leuckocytosis is commonly found in blood

Treatment :

1. Human rabies is incurable
2. Heavy sedation and analgesia given to relieve agonizing symptoms